产品货号：
Z10142
中文名称：
ABCC8抗体
英文名称：
Anti-ABCC8 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ABCC8 Antibody |
| 指标别名 | SUR;HHF1;MRP8;PHHI;SUR1;ABC36;HRINS;TNDM2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,FCM,ICC,IHC-F |
| 基因名称 | ABCC8 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human SUR1 (TIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVTERKA). |
| 实际分子量 | 177KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ATP-binding cassette transporter sub-family C member 8 is a protein that in humans is encoded by the ABCC8 gene.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1,MDR/TAP,MRP,ALD,OABP,GCN20,White).This protein is a member of the MRP subfamily which is involved in multi-drug resistance.This protein functions as a modulator of ATP-sensitive potassium channels and insulin release.Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy,an autosomal recessive disorder of unregulated and high insulin secretion.Mutations have also been associated with non-insulin-dependent diabetes mellitus type II,an autosomal dominant disease of defective insulin secretion.Alternatively spliced transcript variants have been found for this gene. |
| Uniprot ID | Q09428 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry in fixed cells(ICC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells |
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